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Platelet-rich plasma: combinational treatment modalities for musculoskeletal conditions
null
《医学前沿(英文)》 2018年 第12卷 第2期 页码 139-152 doi: 10.1007/s11684-017-0551-6
Current research on common musculoskeletal problems, including osteoarticular conditions, tendinopathies, and muscle injuries, focuses on regenerative translational medicine. Platelet-rich plasma therapies have emerged as a potential approach to enhance tissue repair and regeneration. Platelet-rich plasma application aims to provide supraphysiological concentrations of platelets and optionally leukocytes at injured/pathological tissues mimicking the initial stages of healing. However, the efficacy of platelet-rich plasma is controversial in chronic diseases because patients’ outcomes show partial improvements. Platelet-rich plasma can be customized to specific conditions by selecting the most appropriate formulation and timing for application or by combining platelet-rich plasma with synergistic or complementary treatments. To achieve this goal, researchers should identify and enhance the main mechanisms of healing. In this review, the interactions between platelet-rich plasma and healing mechanisms were addressed and research opportunities for customized treatment modalities were outlined. The development of combinational platelet-rich plasma treatments that can be used safely and effectively to manipulate healing mechanisms would be valuable and would provide insights into the processes involved in physiological healing and pathological failure.
关键词: regenerative medicine joint conditions muscle injuries platelet rich plasma tendinopathy healing mechanisms
Plasma-enabled healing of graphene nano-platelets layer
Xiuqi Fang, Carles Corbella, Denis B. Zolotukhin, Michael Keidar
《化学科学与工程前沿(英文)》 2019年 第13卷 第2期 页码 350-359 doi: 10.1007/s11705-018-1787-7
关键词: graphene platelet networks anodic arc discharge plasma healing scanning electron microscopy Raman spectroscopy
Abivertinib inhibits megakaryocyte differentiation and platelet biogenesis
《医学前沿(英文)》 2022年 第16卷 第3期 页码 416-428 doi: 10.1007/s11684-021-0838-5
关键词: abivertinib Btk inhibitor platelet megakaryocyte megakaryopoiesis thrombopoiesis
Engineering platelet-mimicking drug delivery vehicles
Quanyin Hu, Hunter N. Bomba, Zhen Gu
《化学科学与工程前沿(英文)》 2017年 第11卷 第4期 页码 624-632 doi: 10.1007/s11705-017-1614-6
关键词: drug delivery platelets nanomedicine bio-inspired biomimetic
Yinlong Zhang, Guangna Liu, Jingyan Wei, Guangjun Nie
《医学前沿(英文)》 2018年 第12卷 第6期 页码 667-677 doi: 10.1007/s11684-017-0583-y
关键词: platelet-mimicking delivery systems tumor-associated platelets cancer therapy EPR effect
Guocheng LIU MD, Shouhua YANG MD, Zehua WANG MD,
《医学前沿(英文)》 2009年 第3卷 第4期 页码 447-451 doi: 10.1007/s11684-009-0082-x
关键词: cervical cancer lymphatic vessel density blood vessel density platelet-derived growth factor
ZHANG Huilan, WANG Daowen
《医学前沿(英文)》 2008年 第2卷 第1期 页码 11-14 doi: 10.1007/s11684-008-0003-4
null
《医学前沿(英文)》 2016年 第10卷 第1期 页码 76-84 doi: 10.1007/s11684-015-0426-7
Anti-β2 glycoprotein I (anti-β2GP I ) antibodies are important contributors to thrombosis, especially in patients with antiphospholipid syndrome (APS). However, the mechanism by which anti-β2GP I antibodies are involved in the pathogenesis of thrombosis is not fully understood. In this report, we investigated the role of anti-β2GP I antibodies in complexes with β2GP I as mediators of platelet activation, which can serve as a potential source contributing to thrombosis. We examined the involvement of the apolipoprotein E receptor 2' (apoER2') and glycoprotein I ba (GP I bα) in platelet activation induced by the anti-β2GP I /β2GP I complex. The interaction between the anti-β2GP I /β2GP I complex and platelets was examined using in vitro methods, in which the Fc portion of the antibody was immobilized using protein A coated onto a microtiter plate. Platelet activation was assessed by measuring GP II b/ III a activation and P-selectin expression and thromboxane B2 production as well as p38 mitogen-activated protein kinase phosphorylation. Our results revealed that the anti-β2GP I /β2GP I complex was able to activate platelets, and this activation was inhibited by either the anti-GP I bα antibody or the apoER2' inhibitor. Results showed that the anti-β2GP I /β2GP I complex induced platelet activation via GP I bα and apoER2', which may then contribute to the prothrombotic tendency in APS patients.
关键词: anti-β2GP I /β2GP I complex platelet GP I bα apoER2' thrombosis
Anna Khlyustova, Cédric Labay, Zdenko Machala, Maria-Pau Ginebra, Cristina Canal
《化学科学与工程前沿(英文)》 2019年 第13卷 第2期 页码 238-252 doi: 10.1007/s11705-019-1801-8
Kinetic Monte Carlo simulations of plasma-surface reactions on heterogeneous surfaces
Daniil Marinov
《化学科学与工程前沿(英文)》 2019年 第13卷 第4期 页码 815-822 doi: 10.1007/s11705-019-1837-9
关键词: plasma-surface interaction kinetic Monte Carlo plasma nano technology
From plasma to plasmonics: toward sustainable and clean water production through membranes
《化学科学与工程前沿(英文)》 2023年 第17卷 第12期 页码 1809-1836 doi: 10.1007/s11705-023-2339-3
关键词: water treatment membrane-based process plasma treatment plasma polymerization plasmonic light-to-heat conversion
Atomistic simulations of plasma catalytic processes
Erik C. Neyts
《化学科学与工程前沿(英文)》 2018年 第12卷 第1期 页码 145-154 doi: 10.1007/s11705-017-1674-7
Plasma-catalysis: Is it just a question of scale?
J. Christopher Whitehead
《化学科学与工程前沿(英文)》 2019年 第13卷 第2期 页码 264-273 doi: 10.1007/s11705-019-1794-3
关键词: plasma catalysis plasma-activated catalysis non-thermal plasma CO2 conversion
Rongchang WANG, Xinmin ZHAN, Yalei ZHANG, Jianfu ZHAO
《环境科学与工程前沿(英文)》 2011年 第5卷 第1期 页码 48-56 doi: 10.1007/s11783-011-0305-7
关键词: ammonium-rich wastewater membrane biofilm reactor nitrification redox stratification shortcut nitrogen removal
Submerged arc plasma system combined with ozone oxidation for the treatment of wastewater containing
《环境科学与工程前沿(英文)》 2021年 第15卷 第5期 doi: 10.1007/s11783-020-1384-0
• Submerged arc plasma was introduced in terms of wastewater treatment.
关键词: Thermal plasma Submerged arc plasma Wastewater Ozone Phenol Highly energetic electron
标题 作者 时间 类型 操作
Plasma-enabled healing of graphene nano-platelets layer
Xiuqi Fang, Carles Corbella, Denis B. Zolotukhin, Michael Keidar
期刊论文
Platelet membrane-based and tumor-associated platelet- targeted drug delivery systems for cancer therapy
Yinlong Zhang, Guangna Liu, Jingyan Wei, Guangjun Nie
期刊论文
The relationship between platelet-derived growth factor expression and angiogenesis/lymphangiogenesis
Guocheng LIU MD, Shouhua YANG MD, Zehua WANG MD,
期刊论文
Diagnostic evaluation of plasma aldosterone concentration to plasma renin activity ratio in primary aldosteronism
ZHANG Huilan, WANG Daowen
期刊论文
Anti-β glycoprotein I antibodies in complex with β2 glycoprotein I induce platelet activation via two
null
期刊论文
Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: A brief
Anna Khlyustova, Cédric Labay, Zdenko Machala, Maria-Pau Ginebra, Cristina Canal
期刊论文
Kinetic Monte Carlo simulations of plasma-surface reactions on heterogeneous surfaces
Daniil Marinov
期刊论文
Nitrifying population dynamics in a redox stratified membrane biofilm reactor (RSMBR) for treating ammonium-rich
Rongchang WANG, Xinmin ZHAN, Yalei ZHANG, Jianfu ZHAO
期刊论文